Early life stress (ELS) is associated with a range of negative effects on long-term human health. With increased concerns over child abuse during the COVID-19 pandemic, there is a need for a deeper understanding of how ELS affects immune system programming and development. Neglect is a significant s...
BACKGROUND: Offspring from preeclamptic women have a greater risk of hypertension and cerebrovascular dysfunction later in life. One of the major contributors of cerebrovascular dysfunction is impaired cerebral blood flow (CBF) autoregulation. In the USA, 1 in 25 pregnancies are preeclamptic. Preecl...
Background: One of the most invasive forms of breast cancer is the Triple-Negative Breast Cancer (TNBC). Despite the combination of chemotherapy and immunotherapy among other treatment modalities, patients show limited response mostly due to the highly immunosuppressive tumor microenvironment (TME)....
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) causes coronavirus disease 2019 (COVID-19), which has ignited the most significant health crisis of the 21st century. Acute COVID-19 infection has lethal outcomes and post-acute sequelae of COVID-19 (PASC) infections, commonly called 'long-...
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