IntroductionIn recent years, Black Americans in urban areas have seen a disproportionate rise in opioid drug death rates, with the largest increase from synthetic opioids. As the opioid crisis continues to devastate Black communities, there is an urgent need to tailor strategies, interventions, trea...
Early life stress (ELS) is associated with a range of negative effects on long-term human health. With increased concerns over child abuse during the COVID-19 pandemic, there is a need for a deeper understanding of how ELS affects immune system programming and development. Neglect is a significant s...
Background The aim of this study was to examine the impact of COVID-19 on social determinants of health among African Americans with HIV. The impact of COVID-19 has been devastating for all individuals; however, it poses an increased risk for individuals with chronic health conditions type 2 diabet...
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) causes coronavirus disease 2019 (COVID-19), which has ignited the most significant health crisis of the 21st century. Acute COVID-19 infection has lethal outcomes and post-acute sequelae of COVID-19 (PASC) infections, commonly called 'long-...
Abstract: Background: Childhood obesity is a growing global epidemic, with significant racial, ethnic and socioeconomic disparities. While current efforts to stem the tide of the obesity epidemic have focused on public policy and individual level behaviors, little research has been done on community...
Purpose: Ewing Sarcoma (ES) is a bone and soft tissue cancer affecting young adults and children. ES mostly occurs in the bones or soft tissue of the arms, legs, and pelvis. Localized ES presents with 5-year survival rate of 70%, but metastatic 5-year survival rate is between 15% and 30%. ES has evi...
Background: The social vulnerability index (SVI), developed by the CDC, is a novel social disadvantage metric based on comprehensive data from the U.S. Census Bureau American Community Survey. It includes 15 different social variables organized into the subthemes of socioeconomic status (SES), hous...
Background: High-risk alcohol use and related sexual behavior (i.e., multiple partners, casual sex, sex without condoms/contraception) that may contribute to sexually transmitted infections (STIs) or unintended pregnancies during young adulthood is a significant public health concern. Moreover, wom...
Objective: Women experiencing homelessness are a particularly vulnerable population for unintended pregnancy and sexually transmitted infections, which can then potentially perpetuate the cycle of poverty across the lifecourse. Although women experiencing homelessness may have a strong desire to av...
Background: One of the most invasive forms of breast cancer is the Triple-Negative Breast Cancer (TNBC). Despite the combination of chemotherapy and immunotherapy among other treatment modalities, patients show limited response mostly due to the highly immunosuppressive tumor microenvironment (TME)....
Background: Preventing morbidity and mortality from COVID-19 requires reaching diverse communities. In the U.S., the COVID-19 pandemic disproportionately impacted people of color including Asian Americans, Native Hawaiians, and Pacific Islanders (AANHPI). To prevent severe illness and deaths from CO...
Introduction University of North Texas HSC medical students learn Point of Care Ultrasound (POCUS) in clinical settings as part of their curriculum. In 2021, students provided healthcare screenings and ultrasound scans to hundreds of patients in underserved rural communities in West Texas. Students...
BACKGROUND: Offspring from preeclamptic women have a greater risk of hypertension and cerebrovascular dysfunction later in life. One of the major contributors of cerebrovascular dysfunction is impaired cerebral blood flow (CBF) autoregulation. In the USA, 1 in 25 pregnancies are preeclamptic. Preecl...
Background The opioid epidemic and resulting overdoses have primarily afflicted White communities more than any other ethnic group. However, numbers of opioid related overdoses and ED visits have increased in Black communities in recent years given the rise of fentanyl-laced drugs, cocaine use and ...
BackgroundWhile there have been many devastations from COVID-19, a high prevalence of food insufficiency has been reported, even in developed countries such as the United States (US).4 Low and very low food sufficiency in the US has fluctuated during the COVID-19 pandemic, hitting record highs in De...
The world is aging. Caring for this vulnerable population through age-friendly health systems is imperative for our future. With the universal lack of geriatricians, family physicians primarily care for the elderly population and are therefore ideally placed to lead changes to improve the lives of g...
Background: Currently, there are no preclinical models capable of studying pharmacoethnicity differences of drugs. Hence, health disparities are found with retrospective studies only. The absence of an in-vitro model that studies pharmacoethnicity differences result in negative outcomes for minorit...
Background: Racism has negative associations with the mental and physical health of children and adolescents. It is critical in our pursuit of health equity that the relationships between racial discrimination and health are better understood. Unfortunately, research in this field has been limited...
Background: Subjective memory complaints (SMC) are considered as subjects' interpretation of their cognitive aspects, such as memory and perception. Cardiovascular risk factors (CVRFs) such as hypertension, diabetes, dyslipidemia, and obesity may contribute to cognitive decline and their relationshi...
Background: 2020 brought unprecedented situations around the globe due to Coronavirus disease (Covid-19) caused by the SARS-CoV-2 virus. During the Covid-19 pandemic, the households faced isolation, fear, worry, and anxiety, which led to poor mental health of adults in the US. However, the declinin...
Exercise-induced bronchoconstriction (EIB) is a symptom shared by 90% of individuals diagnosed with asthma, and is typically caused by the inhalation of cold and/or dry air. Since respiratory heat and moisture exchange occurs primarily in the nasal passages, EIB ultimately arises from nasal insuffic...
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